I'm a HUGE comic fan. I've been collecting since I was 5 and I'm now 25. I have nearly a 4,000 comic collection, by the last count on my CCL software. Despite my years of experience, I still stick to Marvel and DC though.
Some Favorite books going right now:
Green Lantern, GL Corps, Justice Society of America, Nova, Ghost Rider, Mighty Avengers
Some All-Time Favorite of the Past:
Green Lantern: Emerald Twilight, Green Lantern: Rebirth, Green Lantern: Sinestro Corps War, Death & Return of Superman, Crisis on Infinite Earths, Kingdom Come, JLA: Rock of Ages, X-Men: Age of Apocalypse, Marvel: Infinity Gauntlet, Avengers: Red Zone, and a ton of others.