I started it last night. Is it me or was that the saddest opening to a game ever? That plague either spread danged fast or the doctors and government had been ignoring it. It makes me wonder what happened to Nate and them from Uncharted since it's the same universe if you take the newspaper about the parasite in Uncharted 3 seriously.
Oh I'm already figuring it's going to end badly leading into the sequels and this thing is guaranteed to have one. It's getting tons of praise and looks amazing. I'm just glad the made pittsburgh look like pittsburgh and not a single bridge a building like fallout 3 did.
Nah, it was just an easter egg in Uncharted. As for the sad part, just wait for the rest of the game (but yeah, that one moment in the opening was sad as hell) The best is yet to come.